The basin of the Cuiabá River, begins in the region of the municipality of Nobres, more abundant due to the affluence of the Manso River, is now called the Cuiabá River, with an average width of 150m, its main tributaries are the Ribeirão Pari and the Manso, São Lourenço and Coxipó.

The Coxipó River passes through the entire municipality of Cuiabá, with its head in the Chapada dos Guimarães National Park, it meets the Cuiabá River in the community of São Gonçalo Beira-Rio, which follows its destination on the way to the Paraguai and Pantanal Rivers.